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    <title>American Journal of Cancer Prevention</title>
    <link>http://www.sciepub.com/journal/AJCP</link>
    <description>American Journal of Cancer Prevention is a peer reviewed, open access journal that publishes original, high-quality, peer-reviewed research on cancer prevention. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of Cancer Prevention.</description>
    <dc:publisher>Science and Education Publishing</dc:publisher>
		<dc:language>en</dc:language>
		<dc:rights>2013 Science and Education Publishing Co. Ltd All rights reserved.</dc:rights>
		<prism:publicationName>American Journal of Cancer Prevention</prism:publicationName>
		12
		1
		January 2025
		<prism:copyright>2013 Science and Education Publishing Co. Ltd All rights reserved.</prism:copyright>
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<title>
Oral Cancer Screening and Public Health Impact: Epidemiology, Technologies, Awareness, and Future Direction
</title>
<link>http://pubs.sciepub.com/ajcp/12/1/1</link>
<description>
<![CDATA[Oral cancer remains a significant global public health challenge, with increasing incidence rates, particularly among younger populations. Despite advancements in treatment, survival outcomes continue to be poor, largely due to delayed diagnosis and limited public awareness. Early detection improves prognosis, enhances survival rates, and minimises treatment-related complications. Most oral cancers are preceded by visible premalignant lesions, making them potentially detectable through routine clinical examinations.Systematic visual and oral examinations have proven to be both practical and effective in identifying early-stage disease in asymptomatic individuals. This review explores the epidemiology and risk factors associated with oral cancer, examines current screening strategies and public health interventions, and discusses future innovations, including salivary diagnostics, artificial intelligence, and mobile health technologies, that may transform early detection and management. Emphasis is placed on the need for multidisciplinary collaboration and improved public and professional awareness to shift the diagnostic window towards earlier stages of the disease.]]>
</description>
<dc:creator>
Sohail  Vyas, Manjiri  Chakor, Hoorieh  Sadat Alamolhoda, Karen  Ojeda, Shilpi  Deshpande, Happy  Parth Shah, Ridhi  Bhola
</dc:creator>
<dc:date>2025-09-18</dc:date>
<dc:publisher>Science and Education Publishing</dc:publisher>
<prism:publicationDate>2025-09-18</prism:publicationDate>
<prism:number>1</prism:number>
<prism:volume>12</prism:volume>
<prism:startingPage>1</prism:startingPage>
<prism:endingPage>8</prism:endingPage>
<prism:doi>10.12691/ajcp-12-1-1</prism:doi>
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<title>
Mutational Difference between the Microsatellite BAT 26 and the TP53 Coding Gene and Survival of Patients with Oral Cavity Cancers in Senegal
</title>
<link>http://pubs.sciepub.com/ajcp/12/1/2</link>
<description>
<![CDATA[Oral cancers primarily present as oral squamous cell carcinoma and are a subgroup of head and neck cancers (HNC). The objective of this study was to identify mutational differences and assess the survival of Senegalese patients with oral cavity cancers. A total of 75 tissue samples from patients and 40 blood samples from healthy controls were analyzed. DNA extraction, polymerase chain reaction (PCR), and sequencing were performed to obtain genetic sequences. The software BioEdit and DnaSP were used to analyze polymorphism and genetic diversity in patients. Chromatograms from the BAT 26 microsatellite and the <i>TP53</i> gene were compared to the consensus sequence and the TP53 reference sequence, respectively, using Mutation Surveyor software. The multivariate Cox analysis was performed using R software, and the impact of BAT 26 instability on patient survival was evaluated using the Kaplan–Meier method with StatView software. The results revealed greater genetic diversity in the <i>TP53 </i>gene than in BAT 26, particularly in terms of the number of polymorphic and informative sites. Furthermore, microsatellite instability appeared to lead to the accumulation of a specific TP53 mutation (c.640C>G p.His214Asp). This study indicates that Senegalese patients with oral cavity cancers harbor more TP53 mutations than BAT 26 mutations. However, BAT 26 instability appeared to confer a survival advantage to patients.]]>
</description>
<dc:creator>
Mame  Diarra Samb, Mbacke  Sembene
</dc:creator>
<dc:date>2025-12-11</dc:date>
<dc:publisher>Science and Education Publishing</dc:publisher>
<prism:publicationDate>2025-12-11</prism:publicationDate>
<prism:number>1</prism:number>
<prism:volume>12</prism:volume>
<prism:startingPage>9</prism:startingPage>
<prism:endingPage>14</prism:endingPage>
<prism:doi>10.12691/ajcp-12-1-2</prism:doi>
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